GENETRON S5 is a new generation of semiconductor sequencer which has been widely used in the field of gene detection because of its simple and direct principle, higher degree of automation and more flexible throughput.

The semiconductor chip is lined with small holes, each of which is a sequencing reaction cell. When a magnetic bead covered by the monoclonal sequence enters the small hole, the sequencing reaction starts: Four bases are passed through in sequence. When the base is inserted, there is a release of H ions, which causes a change in the pH level in the cuvette. The change in pH is induced by the sensor under the reaction cell, which in turn causes a change in potential and voltage, and is finally converted into base information.


Principle of Semiconductor Sequencing

Fast and accurate:No need for specific modified nucleotides, lasers or optical detection equipment, extremely fast detection, accurate sequencing reaction which can be completed within 4 hours

Minimal operation:With automatic database building instrument and modular loading design, manual operation takes less than 45 minutes

Flexible throughput:Can be adapted to 4 chips, high-dimensional throughput, to meet the needs of a variety of clinical testing

Wide range of applications:With Genetron's patented one-step tumor detection reagent, it can detect a variety of tumors   such as central nervous system tumors and respiratory tumors, and be widely used in transcriptome sequencing, 16s metagenomic sequencing, miRNA analysis, and others

Product performance

Work process


Product Parameters

Compatible chipIon 510, 520, 530, 540, and 550 Chips
Size(W*D*H)54.2 x 80.6 x 50.9 cm
Weight63.5 kg
Power supply100–240 VAC, 50/60 Hz, 6.5–14.5 A
Space required by the instrument

top = 30.5 cm  left= 10.0 cm  right = 30.5 cm
front end = 30.5 cm
rear end = 30.5 cm

Working environment

• Temperature:15-30°C (59-86°F)
• Humidity:10-80%,Non-condensing
• Altitude:Up to 2,500 m (8,200 ft)
• Calorific value at 1,200W power consumption: 4,094 BTU/hr

Other connection methods1 GigE Ethernet;2 x USB 2.0;RJ45
Server storage space~24 TB
SoftwareLocalized software and reporting system for easy analysis
Application Kit
NumberProduct NameProduct NumberPlatformSpecifications

Eight-Gene Mutations Detection Kit (semiconductor sequencing technology)


High throughput sequencingFor 24 persons
2Human EGFR gene mutation detection kit
(Semiconductor sequencing)
RSN005High throughput sequencingFor 24 persons
3Human EGFR gene mutation detection kit
(Semiconductor sequencing)
RSN007High throughput sequencingFor 24 persons
4Human brain cancer eight gene detection kit
(Semiconductor sequencing)
RSN008High throughput sequencingFor 24 persons
5Human urothelioma tumor gene detection kit
(Semiconductor sequencing)
RSN009High throughput sequencingFor 24 persons
6Human thyroid full-cycle gene detection kit
(Semiconductor sequencing)
RSN010High throughput sequencingFor 24 persons
7Human breast cancer BRCA1/2 gene detection kit
(Semiconductor sequencing)
RSN011High throughput sequencingFor 24 persons
8Human tumor medication guidance gene detection kit
(Semiconductor sequencing)
RSN012High throughput sequencingFor 24 persons
Supporting instruments and supplies
Product NameType/SpecificationProduct Code
Automatic sample loading systemGENETRON ChefGH003


Compatible chip

on 510, 520, 530, 540, and 550 Chips 

Size(W*D*H)71.4 x 70.0x 56.1 cm (关);71.4 x 70.0x 83.9 cm (开)
Weight68.2 kg
Power supply100–240 VAC,50/60 Hz,6.5–14.5 A 
Space required by the instrument

top = 35.6 cm  left= 10.0 cm  right = 10.0 cm
front end = 17.0 cm
rear end = 10.0 cm

Working environment

• Temperature: 20-25°C (68-77°F)
• Humidity: 40-60%,Non-condensing
• Altitude: Up to 2,000 m (6,500 ft)
• Calorific value at 1,200W power consumption: 4,094 BTU/hr

Other connection methodsEthernet; LAN; RJ45

Sequence Number
Product NameProduct CodePlatformType/Specification
1Sequencing reaction universal kit(S5)RSN006High-throughput sequencing8 reactions / set
Gene and Mutations List

Genetron Health Genetron Health Management
  • USA
  • Beijing
  • Shanghai
  • Chongqing
  • Hangzhou
  • Guangzhou
  • USA

    Genetron Health Technologies Inc.

    6 Davis Drive. Research Triangle Park. North Carolina. U.S.A

    Tel: +1 919 964 3638


  • 1-2/F, Building 11, Zone 1, 8 Life Science Parkway, Changping District, Beijing, China.

    Tel: +86 10 5090 7521


  • 1F,Building 2,111 Gaoyi Road, Baoshan District, Shanghai, China

    Tel:+86 21 6070 5728


  • No.101 Cuibai Rd, Bld No.5, Floor 9, Dadukou District, Chongqing, China

    Tel:+86 23 6891 5807


  • 6F, Innovation China industrial Park, Shenjia Road 319, Xiacheng District, Hangzhou, China

    Tel: +86 571 5650 9193


  • Block 3, No. 6, Nanjiang Second Road, Pearl River Street, Nansha District, Guangzhou, China


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Genetron Health Genetron Health Management